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AMH

Fertility profile Biomarker

Sample Needed

Collection Type: Blood

Body System

Related System: Fertility profile

Overview

Anti-Müllerian hormone (AMH) is a glycoprotein produced by granulosa cells of small growing ovarian follicles and is a marker of the remaining egg (ovarian) reserve. The blood test measures circulating AMH concentration to estimate quantity (not quality) of a woman’s follicle pool. It is used in fertility assessments, to predict response to ovarian stimulation for IVF, and to help diagnose conditions such as polycystic ovary syndrome (PCOS, often high AMH) or diminished ovarian reserve/premature ovarian insufficiency (low AMH). Testing is prompted by infertility, irregular or absent menstrual cycles, or family history of early menopause. AMH falls with age, is low after menopause or ovarian damage, and is generally not useful as a pregnancy test; levels differ by age and sex (primarily interpreted in reproductive-age females).

Test Preparation

  • No special preparation is required

Why Do I Need This Test

  • Profile: included in the Fertility profile.
  • Symptoms indicating testing: difficulty conceiving, irregular or absent periods, poor response to prior fertility treatment, planning fertility preservation.
  • Conditions diagnosed/monitored: ovarian reserve assessment, PCOS screening (supportive), monitoring ovarian function after chemotherapy or surgery.
  • Reasons for abnormal levels: advancing age, ovarian surgery, chemotherapy/radiation, genetic premature ovarian insufficiency, or PCOS.
  • Biological meaning: low AMH = reduced ovarian follicle pool; high AMH = increased follicle count/PCOS.
  • Modifying behaviors/family history: smoking, gonadotoxic treatments, or family history of early menopause/POI increase need for testing.

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Understanding Test Results

  • High values (typically >4.0 ng/mL or >28.6 pmol/L): suggest high ovarian follicle count and are commonly seen with PCOS.
  • High AMH predicts strong ovarian response to stimulation but also increased risk of ovarian hyperstimulation syndrome (OHSS) during fertility treatment.
  • Normal values (about 1.0–4.0 ng/mL or 7.14–28.6 pmol/L): consistent with expected ovarian reserve for many reproductive-age women and a likely normal response to stimulation.
  • Borderline/low values (approx.
  • 0.7–1.0 ng/mL or 5.0–7.14 pmol/L): may indicate diminished ovarian reserve and a potentially reduced response to stimulation; warrants counseling about fertility planning.
  • Low/very low values (<0.3–0.7 ng/mL or <2.1–5.0 pmol/L): indicate significantly reduced ovarian reserve, higher risk of poor response to IVF, and increased likelihood of earlier menopause or premature ovarian insufficiency.
  • Undetectable or trace levels (<0.1 ng/mL or <0.7 pmol/L): consistent with menopause or near-complete loss of ovarian follicles.
  • Interpretation should consider assay-specific cutoffs; results are best used with age, antral follicle count (AFC), and other reproductive markers (FSH, estradiol) to guide clinical decisions.

Normal Range

1.0-4.0 ng/mL OR 7.14-28.6 pmol/L

FAQs

Q: What is a good AMH level to get pregnant?

A: Anti‑Müllerian hormone (AMH) reflects ovarian reserve. Generally, >3.0 ng/mL is high, 1.0–3.0 ng/mL is considered adequate/good for conception, 0.5–1.0 ng/mL suggests reduced reserve, and <0.5 ng/mL indicates low reserve. AMH varies with age and doesn’t guarantee pregnancy; it’s one part of fertility assessment alongside other factors like partner fertility.

Q: What is a good AMH level for age 35?

A: At age 35, a \

Q: What is a normal AMH level?

A: A normal AMH level for reproductive-age women is roughly 1.0–4.0 ng/mL (≈7–29 pmol/L). Levels above this suggest higher ovarian reserve (often seen with PCOS); levels below about 1.0 ng/mL indicate reduced ovarian reserve, with very low <0.3 ng/mL. AMH declines with age and lab reference ranges vary, so discuss results with a clinician for personal interpretation.

Q: What does the AMH hormone do?

A: Anti‑Müllerian hormone (AMH) is produced by ovarian granulosa cells and reflects the number of growing (pre‑antral and antral) follicles a marker of ovarian reserve. It helps estimate remaining egg supply and predict response to fertility treatments; levels fall with age and are relatively cycle‑independent. In males, fetal AMH from Sertoli cells causes regression of Müllerian ducts.

Q: Can vitamin D increase AMH?

A: Vitamin D has been linked to ovarian function and some observational studies report higher AMH with adequate vitamin D. Randomized trials are inconsistent: supplementation may modestly raise AMH in deficient women, but evidence is insufficient to conclude vitamin D reliably increases AMH or ovarian reserve. Correct vitamin D deficiency for overall health, and discuss testing/supplementation with your healthcare provider.

Q: Which fruits increase AMH level?

A: No specific fruit has been proven to directly increase AMH levels. However, a diet rich in antioxidant‑packed fruits—especially berries, pomegranate, citrus and apples—may support ovarian health and reduce oxidative stress. Eating a balanced diet, maintaining healthy weight, avoiding smoking and managing stress are more likely to preserve ovarian reserve than relying on any single fruit.

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